Features of Antibiotics Challenges Mechanisms Opportunities PDF
Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. Antibiotics Challenges Mechanisms Opportunities PDF
This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics.
Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions:
- What are antibiotics?
- Where do antibiotics come from?
- How do antibiotics work?
- Why do antibiotics stop working?
- How should our limited inventory of effective antibiotics be addressed?
Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.
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Description of Antibiotics Challenges Mechanisms Opportunities PDF
Health, anatomy, physiology, biochemistry, medicine, surgery, and nursing textbooks will likely be at your side throughout your medical studies, and you’ll be reading through countless scientific papers, but you might want to read something beforehand that gives you insight into the world of medicine in practice – whether that’s research, at the clinic or in the operating room. The most featured and reviewed on book “Book name PDF” is available for grabs now here on our website free for students and professionals sole purpose of teaching and education. It has been boasted and proven with thousands of user reviews that it has all the information to make you one of the highly qualified professionals in the world of medicine and its branches. Without a doubt a masterpiece for those who aspire to be doctors or heal those they find in ailment. It is a must read again and again for everyone that can get their hands on this limited edition book.
The Authors
Christopher Walsh is a Harvard Medical School professor emeritus who serves as a senior advisor to the ChEM-H Center at Stanford University. He has authored hundreds of papers and books, including the predecessor to this title, Antibiotics: Origins, Actions, Resistance (2003). Dr. Walsh is a member of the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, the American Academy of Arts and Sciences, and the American Philosophical Society and a co-recipient of the 2010 Welch Prize in Chemistry.
Timothy Wencewicz is a faculty member in the Department of Chemistry at Washington University in St. Louis. After receiving his PhD at the University of Notre Dame, he was a postdoctoral fellow in Christopher Walsh s laboratory at the Harvard Medical School. Dr. Wencewicz s research centers on antibiotic drug discovery, natural product biosynthesis, and targeted drug delivery across bacterial membranes. –This text refers to an alternate kindle_edition edition.
Dimensions and Characteristics of Antibiotics Challenges Mechanisms Opportunities PDF
- Identification Number : B0846851V1
- Publisher : ASM Press; 2nd edition (1 February 2016)
- Language : English
- File size : 41149 KB
- Text-to-Speech : Enabled
- Screen Reader : Supported
- Enhanced typesetting : Enabled
- X-Ray : Not Enabled
- Word Wise : Not Enabled
- Print length : 887 pages
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