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Attributes of The Multifaceted Role of Macrophages in Health and Disease Part B PDF
The Multifaceted Role of Macrophages in Health and Disease Part B PDF Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development. New chapters cover The role of salivary gland macrophages in infection, disease and repair, Reprogramming or replacing brain macrophages to treat neurodegenerative disease, Targeting macrophages for cancer immunotherapy, Heart Macrophages at steady-state and disease: simple bystanders or active players?, Macrophages in the liver, and Developmental programming of macrophages.
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Contents of the Textbook
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: The role of salivary gland macrophages in infection, disease and repair
- Abstract
- 1: Introduction
- 2: Salivary gland structure
- 3: Salivary gland macrophage characterization
- 4: Salivary gland macrophage maintenance
- 5: Salivary gland macrophages in infection
- 6: Salivary gland macrophages in disease
- 7: The role of salivary gland macrophages in development
- 8: The role of salivary gland macrophages in repair and regeneration
- 9: Macrophages in salivary gland cancer and immunotherapy
- 10: The macrophage niche
- 11: Conclusions and future perspectives
- Acknowledgments
- References
- Chapter Two: Mertk: An emerging target in cancer biology and immuno-oncology
- Abstract
- 1: Introduction
- 2: Consequences of Mertk activation
- 3: Immunology of Mertk activation
- 4: Rationale for targeting Mertk as a therapeutic
- 5: Therapeutic strategies and current progress
- 6: Concluding remarks and future perspectives
- References
- Chapter Three: Targeting tumor-associated macrophages for cancer immunotherapy
- Abstract
- 1: Macrophages
- 2: Subclasses of macrophages
- 3: Macrophages in diseases
- 4: Macrophages in cancer: Tumor-associated macrophages
- 5: Clinical significance of TAMs
- 6: Therapeutic strategies to target TAMs
- 7: Rational combination of TAM-targeting therapeutics with conventional therapies
- 8: Discussion
- References
- Chapter Four: Macrophages in the heart: Active players or simple bystanders?
- Abstract
- 1: Introduction
- 2: Healthy heart
- 3: Cardiac resident macrophages’ functions at steady-state
- 4: Dysfunctional heart
- 5: Open questions and concluding remarks
- References
- Chapter Five: Macrophages as key regulators of liver health and disease
- Abstract
- 1: Introduction
- 2: Macrophage heterogeneity in the healthy liver
- 3: Macrophages in acute liver injury
- 4: Macrophages in chronic liver injury
- 5: Macrophages in hepatocellular carcinoma
- 6: Therapeutic targeting of liver macrophages
- 7: Summary and future perspectives
- References
- Chapter Six: Developmental programming of macrophages by early life adversity
- Abstract
- 1: Macrophages
- 2: Developmental programming
- 3: Macrophage programming
- 4: Concluding remarks and open questions
The Writers
After defending an experimental thesis on malignant haematopoiesis, Samanta Mariani obtained a Master’s Degree in Medical Biotechnology from the University of Modena and Reggio Emilia (Italy). She then moved to Milan to join an international PhD programme on Cellular and Molecular Biology held by the Vita-Salute San Raffaele University and the Open University of London. During the four years of her PhD in Professor Guido Poli’s laboratory, she worked on HIV-1 biology. After successfully defending her PhD thesis, she decided to move to the United States to experience a new research environment and broaden her scientific expertise. Changing scientific topics between the Master’s and PhD led to her fascination in human haematopoiesis and the desire to find a postdoc in that field.
Proportions of The Multifaceted Role of Macrophages in Health and Disease Part B PDF
- No. of pages: 268
- Language: English
- Copyright: © Academic Press 2022
- Published: May 20, 2022
- Imprint: Academic Press
- Hardcover International Standard Book Number: 9780323907439
- eBook International Standard Book Number: 9780323907446
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