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600This article contains some pharmacology made ridiculously easy mnemonics for all medical students, especially those in their 3rd year going through this hell in the form of a subject name pharmacology.
- Sulfonamides: common characteristics SULFA:S-Steven-Johnson syndrome/ Skin rash / Solubility low
U-Urine precipitation/ Useful for UTI
L-Large spectrum (gram positives and negatives)
F-Folic acids synthesis blocker (as well as synthesis of nucleic acids)
A-Analog of PABA -
Diuretics: groups“Leak Over The CAN“:
L-Loop diuretics
O-Osmotics
T-Thiazides
C-Carbonic anhydrase inhibitors
A-Aldosterone inhibitors
N-Na (sodium) channel blockers -
Tuberculosis: treatment If you forget your TB drugs, you’ll
die and might need a PRIEST“:
P-Pyrazinamide
R-Rifampin
I-Isoniazid (INH)
E-Ethambutol
St-Streptomycin -
Aminoglycosides: common characteristics AMINO
- Active Against Aerobic gram negative
Mechanism of resistance are Modifying enzymes
Inhibit protein synthesis by binding to 30S subunit
Nephrotoxic
Ototoxic -
Femara (Letrozole) Side Effects
Just Remember “FEMARA”
F-Fracture (Bone), Flushes (Hot)
E-Edema (Peripheral)
M-Memory impairment(Less Common)
A-Anxiety (Less Common)
R-Raised Sweating
A-Arterial thrombosis(very rare)
- Thalidomide: effect on cancer cells“Thalidomide
makes the blood vessels hide“:
Use thalidomide to stop cancer cells from growing new blood vessels. - Carbamazepine (CBZ): useCBZ:
C-Cranial Nerve V (trigeminal) neuralgia
B-Bipolar disorder
Z-Seizures - Warfarin: interactionsACADEMIC QACS:
A-Amiodarone
C-Cimetidine
A-Aspirin
D-Dapsone
E-Erythromycin
M-Metronidazole
I-Indomethacin
C-Clofibrates
Q-Quinidine
A-Azapropazone
C-Ciprofloxacin
S-Statins -
Morphine: side-effects MORPHINE:
M-Myosis
O-Out of it (sedation)
R-Respiratory depression
P-Pneumonia (aspiration)
H-Hypotension
I-Infrequency (constipation, urinary retention)
N-Nausea
E-Emesis -
Tricyclic antidepressants (TCA): side effectsTCA’S:
T-Thrombocytopenia
C-Cardiac (arrhythmia, MI, stroke)
A-Anticholinergic (tachycardia, urinary retention, etc)
S-Seizures -
Corticosteroids: adverse side effectsCUSHINGS BAD MD:
C-Cataracts
U-Up all night (sleep disturbances)
S-Suppression of HPA axis
H-Hypertension/ buffalo Hump
I-Infections
N-Necrosis (avascular)
G-Gain weight
S-Striae
B-Bone loss (osteoporosis)
A-Acne
D-Diabetes
M-Myopathy, moon faces
D-Depression and emotional changes -
Microtubules: drugs that act on microtubules.“The
MicroTubule Growth Voiding Chemicals”:
T-Thiabendazole
M-Mebendazole
T-Taxol
G-Griseofulvin
V-Vincristine/ Vinblastine
C-Colchicine
BromoCRYPTine is a DOPamine agonist. -
Beta blockers: members“The NEPAL Prime
M-Minister”:
T-Timolol
N-Nadolol
E-Esmolol
P-Pindolol
A-Atenolol
L-Labetalol
P-Propranolol
M-Metoprolol -
Insulin: mixing regular insulin and NPH“Not Ready
Ready Now”:
Air into NPH
Air into Regular
Draw up Regular
Draw up NPH -
Parasympathetic vs. sympathetic neurotransmitters“No
sympathy for a Pair of Aces”:
Norepinephren is secreted in by the Sympathetic nervous system
while Acetylcholine is secreted in the Parasympathetic nervous -
Benzodiazepines: 3 members that undergo extrahepatic metabolism
“Outside The Liver”:
O-Oxazepam
T-Temazepam
L-Lorazepam
These undergo extrahepatic metabolism and do not form active metabolites. - Guanethidine: mechanism Guanethidine prevents NE
(norepinephrine) release. - Opioids: mu receptor effects“MD CARES“:
M-Miosis
D-Dependency
C-Constipation
A-Analgesics
R-Respiratory depression
E-Euphoria
S-Sedation
-
Adrenoceptors: vasomotor function of alpha vs. betaABCD:
Alpha = C
Beta = Dilate. -
Beta 1 selective blockers“BEAM ONEup, Scotty”:
Beta 1 blockers:
E-Esmolol
A-Atenolol
M-Metropolol -
Atropine use: tachycardia or bradycardia“A goes with B“:
Atropine used clinically to treat B
- Cancer drugs: time of action between DNA->mRNAABCDEF:
A-Alkylating agents
B-Bleomycin
C-Cisplastin
D-Dactinomycin/ Doxorubicin
E-Etoposide
F-Flutamide and other steroids or their antagonists (eg tamoxifen,
leuprolide) - Busulfan: featuresABCDEF:
A-Alkylating agent
B-Bone marrow suppression s/e
C-CML indication
D-Dark skin (hyperpigmentation) s/e
E-Endrocrine insufficiency (adrenal) s/e
F-Fibrosis (pulmonary) s/e - Tricyclic antidepressants: members worth knowing“I have to
hide, the CIAis after me”:
C-Clomipramine
I-Imipramine
A-Amitrptyline - Torsades de Pointes: drugs causingAPACHE:
A-Amiodarone
P-Procainamide
A-Arsenium
C-Cisapride
H-Haloperidol
E-Eritromycin - Asthma drugs: leukotriene inhibitor actionzAfirlukast:
Antagonist of lipoxygenase
zIlueton: Inhibitor of LT receptor - Propranolol and related ‘-olol’ drugs: usage“olol”
is just two backwards lower case b’s.
Backward b’s stand for “beta blocker”.
Beta blockers include acebutolol, betaxolol, bisoprolol,
oxprenolol, propranolol. - Beta blockers: B1 selective vs. B1-B2 non-selectiveA
through N: B1 selective: Acebutalol, Atenolol, Esmolol, Metoprolol.
O through Z: B1, B2 non-selective:Pindolol, Propanalol, Timolol. - Antirheumatic agents (disease modifying): membersCHAMP:
C-Cyclophosphamide
H-Hydroxycloroquine and choloroquinine
A-Auranofin and other gold compounds
M-Methotrexate
P-Penicillamine - HMG-CoA reductase inhibitors (statins): side effects,
contraindications, interactionsHMG–CoA:
Side effects:
H-Hepatotoxicity
M-Myositis [aka rhabdomyolysis] · Contraindications:
G-Girl during pregnancy/ Growing children
· Interactions:
C-Coumarin/ Cyclosporine - Serotonin syndrome: componentsCauses HARM:
H-Hyperthermia
A-Autonomic instability (delirium)
R-Rigidity
M-Myoclonus - Therapeutic index: formulaTILE:
TI= LD50 / ED50 - Antiarrhythmics: class III membersBIAS:
B-Bretylium
I-Ibutilide
A-Amiodarone
S-Sotalol - MAOIs: indicationsMAOI‘S:
M-Melancholic [classic name for atypical depression] A-Anxiety
O-Obesity disorders [anorexia, bulemia] I-Imagined illnesses [hypochondria] S-Social phobias - K+ increasing agentsK-BANK:
K-K-sparing diuretic
B-Beta blocker
A-ACEI
N-NSAID
K-Ksupplement - Ribavirin: indicationsRIBAvirin:
R-RSV
I-Influenza B
A-Arenaviruses (Lassa, Bolivian, etc.) - SIADH-inducing drugsABCD:
A-Analgesics: opioids, NSAIDs
B-Barbiturates
C-Cyclophosphamide/ Chlorpromazine/ Carbamazepine
D-Diuretic (thiazide) - Diuretics: thiazides: indications“CHIC to use
thiazides”:
C-CHF
H-Hypertension
I-Insipidous
C-Calcium calculi - Parkinsonism: drugsSALAD:
S-Selegiline
A-Anticholinenergics (trihexyphenidyl, benzhexol, ophenadrine)
L-L-Dopa + peripheral decarboxylase inhibitor (carbidopa, benserazide)
A-Amantadine
D-Dopamine postsynaptic receptor agonists (bromocriptine, lisuride,
pergolide) - Thrombolytic agentsUSA:
U-Urokinase
S-Streptokinase
A-Alteplase (tPA) - Morphine: effects at mu receptorPEAR:
P-Physical dependence
E-Euphoria
A-Analgesia
R-Respiratory depression - Morphine: effectsMORPHINES:
M-Miosis
O-Orthostatic hypotension
R-Respiratory depression
P-Pain supression
H-Histamine release/ Hormonal alterations
I-Increased ICT
N-Nausea
E-Euphoria
S-Sedation - Anticholinergic side effects“Know the ABCD’Sof
anticholinergic side effects”:
A-Anorexia
B-Blurry vision
D-Constipation/ Confusion
D-Dry Mouth
D-Sedation/ Stasis of urine - Antiarrhythmics: classification I to IVMBA College
In order of class I to IV:
M-Membrane stabilizers (class I)
B-Beta blockers
A-Action potential widening agents
C-Calcium channel blockers - Teratogenic drugs“W/ TERATOgenic”:
W-Warfarin
T-Thalidomide
E-Epileptic drugs: phenytoin, valproate, carbamazepine
R-Retinoid
A-ACE inhibitor
T-Third element: lithium
O-OCP and other hormones (eg danazol) - Epilepsy types, drugs of choice“Military General
Attacked Weary Fighters Pronouncing ‘Veni
Vedi Veci’ After Crushing Enemies”:
Epilepsy types:
M-Myoclonic
G-Grand mal
A-Atonic
W-West syndrome
F-Focal
P-Petit mal (absence)
· Respective drugsy:
V-Valproate
V-Valproate
VValproate
A-ACTH
C-Carbamazepine
E-Ethosuximide - Pulmonary infiltrations inducing drugs“Go BAN Me!”:
Go-Gold
B-Bleomycin/ Busulphan/ BCNU
A-Amiodarone/ Acyclovir/ Azathioprine
N-Nitrofurantoin
M-Melphalan/ Methotrexate/ Methysergide - Respiratory depression inducing drugs“STOP
breathing”:
S-Sedatives and hypnotics
T-Trimethoprim
O-Opiates
P-Polymyxins - Benzodiazapines: ones not metabolized by the liver (safe to use in
liver failure)LOT:
L-Lorazepam
O-Oxazepam
T-Temazepam - TB: antibiotics usedSTRIPE:
St-STreptomycin
R-Rifampicin
I-Isoniazid
P-Pyrizinamide
E-Ethambutol - Vigabatrin: mechanismVi-GABA–Tr–In:
Via GABATransferase Inhibition - Propythiouracil (PTU): mechanismIt inhibits PTU:
P-Peroxidase/ Peripheral deiodination
T-Tyrosine iodination
U-Union (coupling) - Beta-blockers: nonselective beta-blockers“TimPinches
His Nasal Problem” (because he has a runny nose…):
Tim-Timolol
Pin-Pindolol
His-Hismolol
Na-Naldolol
Pro-Propranolol - Enoxaparin (prototype low molecular weight heparin): action,
monitoringEnoXaprin only acts on factor Xa.
Monitor Xaconcentration, rather than APTT. - Nicotinic effectsMTWTF(days of week):
M-Mydriasis/ Muscle cramps
T-Tachycardia
W-Weakness
T-Twitching
H-Hypertension/ Hyperglycemia
F-Fasiculation - Muscarinic effectsSLUG BAM:
S-Salivation/ Secretions/ Sweating
L-Lacrimation
U-Urination
G-Gastrointestinal upset
B-Bradycardia/ Bronchoconstriction/ Bowel movement
A-Abdominal cramps/ Anorexia
M-Miosis - Hypertension: treatmentABCD:
ACE inhibitors/ AngII antagonists (sometimes Alpha agonists
also)
B-Beta blockers
C-Calcium antagonists
D-Diuretics (sometimes vasoDilators also) - Phenytoin: adverse effectsPHENYTOIN:
P-P-450 interactions
H-Hirsutism
EEnlarged gums
N-Nystagmus
Y-Yellow-browning of skin
T-Teratogenicity
O-Osteomalacia
I-Interference with B12 metabolism (hence anemia)
N-Neuropathies: vertigo, ataxia, headache - Gynaecomastia-causing drugsDISCOS:
D-Digoxin
I-Isoniazid
S-Spironolactone
C-Cimetidine
O-Oestrogens
S-Stilboestrol - Amiodarone: action, side effects6 P’s:
P-Prolongs action potential duration
P-Photosensitivity
P-Pigmentation of skin
P-Peripheral neuropathy
PPulmonary alveolitis and fibrosis
P-Peripheral conversion of T4 to T3 is inhibited -> hypothyroidis - Beta blockers with intrinsic sympathomimetic activity
Picture diabeticand asthmatickids riding away on a cart
that rolls on pin
Pindolol and Carteolol have high and moderate ISA respectively,
making them acceptable for use in some diabetics or asthmatics despite the fact that they are non-seletive beta blockers. - Physostigmine vs. neostigmineLMNOP:
L-Lipid soluble
M-Miotic
N-Natural
O-Orally absorbed well
P-Physostigmine
Neostigmine, on the contrary, is:
Water soluble
Used in myesthenia gravis
Synthetic
Poor oral absorption - Monoamine oxidase inhibitors: members“PITof
despair”:
P-Phenelzine
I-Isocarboxazid
T-Tranylcypromine
A pit of despair, since MAOs treat depression. - Antibiotics contraindicated during pregnancyMCAT:
M-Metronidazole
C-Chloramphenicol
A-Aminoglycoside
T-Tetracycline - Etoposide: action, indications, side effect“eTOPoside”:
Action:
Inhibits TOPoisomerase II
· Indications:
T-Testicular carcinoma
O-Oat cell carcinoma of lung
P-Prostate carcinoma
· Side effect:
Affects TOPof your head, causing alopecia - Antimuscarinics: members, action“Inhibits Parasympathetic
And Sweat”:
I-Ipratropium
P-Pirenzepine
A-Atropine
S-Scopolamine
Muscarinic receptors at all parasympathetic endings sweat glands in
sympathetic. - Lithium: side effectsLITHIUM:
L-Leukocytes Increased (leukocytosis)
T-Tremors
H-Hypothyroidism
I-Increased Urine
M-Moms beware (teratogenic) - Osmotic diuretics: membersGUM:
G-Glycerol
U-Urea
M-Mannitol - Narcotics: side effects“SCRAM if you see a drug
dealer”:
S-Synergistic CNS depression with other drugs
C-Constipation
R-Respiratory depression
A-Addiction
M-Miosis - Benzodiazepines: antidote“Ben is off with the
flu“:
Benzodiazepine effects off with Flu - SSRIs: side effectsSSRI:
S-Serotonin syndrome
S-Stimulate CNS
R-Reproductive disfunctions in male
I-Insomnia - Depression: 5 drugs causing itPROMS:
P-Propranolol
R-Reserpine
O-Oral contraceptives
M-Methyldopa
S-Steroids - Sex hormone drugs: male“Feminine Males Need
Testosterone“:
F-Fluoxymesterone
M-Methyltestosterone
N-Nandrolone
Testosterone - Ca++ channel blockers: usesCA++ MASH:
C-Cerebral vasospasm/ CHF
A-Angina
M-Migranes
A-Atrial flutter, fibrillation
S-Supraventricular tachycardia
H-Hypertension - Benzodiazepenes: drugs which decrease their metabolism“I‘m Overly Calm”:
I-Isoniazid
O-Oral contraceptive pills
C-Cimetidine - Warfarin: metabolismSLOW:
Has a slowonset of action.
· A quicK Vitamin K antagonist, though.
S-Small lipid-soluble molecule
L-Liver: site of action
O-Oral route of administration.
W-Warfarin - Opioids: effectsBAD AMERICANS:
B-Bradycardia & hypotension
A-Anorexia
D-Diminished pupilary size
A-Analgesics
M-Miosis
E-Euphoria
R-Respiratory depression
I-Increased smooth muscle activity (biliary tract constriction)
C-Constipation
A-Ameliorate cough reflex
N-Nausea and vomiting
S-Sedations - Tetracycline: teratogenicityTEtracycline is a
TE-TEratogen that causes staining of
TEeth in the newborn. - Myasthenia gravis: edrophonium vs. pyridostigmineeDrophonium
is for D
pyRIDostigmine is to get RIDof symptoms. - Narcotic antagonistsThe Narcotic Antagonists
are NAloxone and NA
· Important clinically to treat narcotic overdose. - Inhalation anestheticsSHINE:
S-Sevoflurane
H-Halothane
I-Isoflurane
N-Nitrous oxide
E-Enflurane - Disulfiram-like reaction inducing drugs“PM PMT” as
in Pre Medical Test in the PM:
P-Procarbazine
M-Metronidazole
PMT-Cefo (Perazone, Mandole, Tetan). - Delerium-causing drugsACUTE CHANGE IN MS:
A-Antibiotics (biaxin, penicillin, ciprofloxacin)
C-Cardiac drugs (digoxin, lidocaine)
U-Urinary incontinence drugs (anticholinergics)
T-Theophylline
E-Ethanol
C-Corticosteroids
H-H2 blockers
A-Antiparkinsonian drugs
N-Narcotics (esp. mepridine)
G-Geriatric psychiatric drugs
E-ENT drugs
I-Insomnia drugs
N-NSAIDs (eg indomethacin, naproxin)
M-Muscle relaxants
S-Seizure medicines - Direct sympathomimetic catecholaminesDINED:
D-Dopamine
I-Isoproterenol
N-Norepinephrine
E-Epinephrine
D-Dobutamine - Nitrofurantoin: major side effectsNitroFurAntoin:
N-Neuropathy (peripheral neuropathy)
F-Fibrosis (pulmonary fibrosis)
A-Anemia (hemolytic anemia) - Methyldopa: side effectsMETHYLDOPA:
M-Mental retardation
E-Electrolyte imbalance
T-Tolerance
H-Headache/ Hepatotoxicity
psYcological upset
L-Lactation in female
D-Dry mouth
O-Oedema
P-Parkinsonism
A-Anaemia (haemolytic) - Steroids: side effectsBECLOMETHASONE:
B-Buffalo hump
E-Easy bruising
C-Cataracts
L-Larger appetite
O-Obesity
M-Moonface
E-Euphoria
T-Thin arms & legs
H-Hypertension/ Hyperglycaemia
A-Avascular necrosis of femoral head
S-Skin thinning
O-Osteoporosis
N-Negative nitrogen balance
E-Emotional liability - Sodium valproate: side effectsVALPROATE:
V-Vomiting
A-Alopecia
L-Liver toxicity
P-Pancreatitis/ Pancytopenia
R-Retention of fats (weight gain)
O-Oedema (peripheral oedema)
A-Appetite increase
T-Tremor
E-Enzyme inducer (liver) - Lithium: side effectsLITH:
L-Leukocytosis
I-Insipidus [diabetes insipidus, tied to polyuria] T-Tremor/ Teratogenesis
H-Hypothyroidism - Lead poisoning: presentationABCDEFG:
A-Anemia
B-Basophilic stripping
C-Colicky pain
D-Diarrhea
E-Encephalopathy
F-Foot drop
G-Gum (lead line) - Beta-blockers: main contraindications, cautionsABCDE:
A-Asthma
B-Block (heart block)
C-COPD
D-Diabetes mellitus
E-Electrolyte (hyperkalemia) - Metabolism enzyme inducers“Randy’s Black Car
Goes Putt Putt and Smokes“:
R-Rifampin
B-Barbiturates
C-Carbamazepine
G-Grisoefulvin
P-Phenytoin
P-Phenobarb - Cholinergics (eg organophosphates): effectsIf you know
these, you will be “LESS DUMB“:
L-Lacrimation
E-Excitation of nicotinic synapses
S-Salivation
S-Sweating
D-Diarrhea
U-Urination
M-Micturition
B-Bronchoconstriction - Routes of entry: most rapid ways meds/toxins enter body“Stick
it, Sniff it, Suck it, Soak it”:
Stick = Injection
Sniff = inhalation
Suck = ingestion
Soak = absorption - Hepatic necrosis: drugs causing focal to massive necrosis“Very
A-Angry Hepatocytes”:
V-Valproic acid
A-Acetaminophen
H-Halothane - Bleomycin: action“Bleo–Mycin Blows
MyDNA to bits”:
Bleomycin works by fragmenting DNA (blowing it to bits).
MyDNA signals that its used for cancer (targeting self cells). - Beta-1 vs Beta-2 receptor location“You have 1 heart
and 2 lungs“:
Beta-1are therefore primarily on heart.
Beta-2 primarily on lungs. - Beta-blockers: side effects“BBCLoses Viewers
In Rochedale”:
B-Bradycardia
B-Bronchoconstriction
C-Claudication
L-Lipids
V-Vivid dreams & nightmares
I- -ve Inotropic action
R-Reduced sensitivity to hypoglycaemia - Cisplatin: major side effect, action“Ci-Splat–In“:
Major side effect: Splat(vomiting sound)–vomiting so severe that
anti-nausea drug needed.
Action: Goes Into the DNA strand. - Ipratropium: actionAtropine is buried in the middle:
iprAtropium, so it behaves like Atropine.
These are all the Pharmacology made ridiculously easy mnemonics for now. tune in for more. here are some mnemonics on
general surgery in the meantime.
I want arup kumar majhi obs and gynae bedside clinics booka