Page Contents
Attributes of Bioactive Carboxylic Compound Classes PDF
Following the successful and proven concept used in “Bioactive Heterocyclic Compound Classes” by the same editors, this book is the first to present approved pharmaceutical and agrochemical compounds classified by their carboxylic acid functionality in one handy volume. Bioactive Carboxylic Compound Classes PDF
Each of the around 40 chapters describes one or two typical syntheses of a specific compound class and provides concise information on the history of development, mode of action, biological activity and field of application, as well as structure-activity relationships. In addition, similarities and differences between pharmaceuticals and agrochemicals are discussed in the introduction.
Written by a team of experts in the field, this is a useful reference for researchers in academia and chemical or pharmaceutical companies working in the field of total synthesis and natural product chemistry, drug development, and crop protection research.
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Illustrations of Bioactive Carboxylic Compound Classes PDF
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The Writers
Clemens Lamberth is a senior team leader in the crop protection research department of Syngenta AG, Switzerland. He studied chemistry at the Technical University of Darmstadt, Germany, where he obtained his Ph.D. under the supervision of Prof. Bernd Giese in 1990. Subsequently, he spent one and a half years as a postdoctoral fellow in the group of Prof. Mark Bednarski at the University of California at Berkeley, USA. In 1992 he joined the agrochemical research department of Sandoz Agro AG, Switzerland, which is today, after two mergers, part of Syngenta Crop Protection AG. Since 22 years he is specialized in fungicide discovery. He is the author of more than 130 publications and patents and inventor of Syngenta’s fungicide mandipropamid (Revus®, Pergado®).
Jürgen Dinges is a senior principal research scientist in the pharmaceutical research department at Abbvie, USA. He studied chemistry at the Technical University of Darmstadt, Germany, where he obtained his Ph.D. degree in organic chemistry and chemical engineering under the supervision of Prof. Frieder W. Lichtenthaler in 1991. After being awarded a Feodor-Lynen scholarship from the Humboldt foundation, he spent 18 months as a postdoctoral fellow in the group of Prof. William G. Dauben at the University of California at Berkeley, USA. In 1993 he joined the Department for Biochemistry at Syntex, USA, which today is part of Hoffmann-La Roche Ltd., Switzerland. In 1995 he joined the pharmaceutical research department at Abbott Laboratories, USA, which became part of Abbvie in 2013. Since 19 years he is specialized in drug discovery. He is an author on 57 publications and patents and a co-inventor of more than 10 clinical drug development candidates.
Proportions of Bioactive Carboxylic Compound Classes PDF
- Identification Number : B01HFN4BAO
- Publisher : Wiley-VCH; 1st edition (June 21, 2016)
- Publication date : June 21, 2016
- Language : English
- File size : 25674 KB
- Text-to-Speech : Enabled
- Screen Reader : Supported
- Enhanced typesetting : Enabled
- X-Ray : Not Enabled
- Word Wise : Not Enabled
- Print length : 481 pages
- Lending : Enabled
Reviews From Customers
Pisces51
DISAPPOINTING EARLY WORK BY DEAVER, ONE OF MY FAVORITE AUTHORS WRITING TODAY
November 9, 2020
MY REVIEW 3.5 STARS***
I have been a huge fan of Deaver’s since the ‘90s and had been wanting to read this early novel of his for quite some time. I waited for it to be featured in a promotional email at a sale price but that didn’t happen. Recently just hit the “Purchase” button and paid the full retail price. This book was published two decades ago and since the foundation of the plot line is modern computer technology and the evolution of social media platforms, I would hazard a guess that many readers would gloss right over this early work.
Deaver is by no means the first author to flex his creative muscles to imagine a deadly downside to the rise of the machines. He correctly calculated that the growth of the internet and the pervasiveness of social media in people’s lives could logically pose genuine dangers to the world’s growingly tech savvy population. In this novel penned in 2001 Deaver depicts the status of computer industry and its technology at the beginning of the new millennium. The master story teller both informs and educates the reader with a fascinating fact based journey which chronicles the historical events and timelines that marked the rise of the computer industry. He accurately depicts the computer age and the surge of social media which were topical at the time he was writing the novel. The narrative is interesting, factual, and is replete with the terminology of the computer savvy population of that period in our history.
I read the final half of the book but never changed my opinion that I felt the novel was a big letdown. That is likely in large part because I love Deaver, I had actually been looking forward to reading this particular early work, and thirdly, I had expected the master story teller and master of misdirection to render a chilling portrait of the cold, narcissistic predator who had lost touch with reality and could no longer distinguish a digital player in a computer game from a living flesh and blood person. There was actually a fourth reason that this book disappointed. Did it contain Deaver’s “signature plot twists”? Yes, it did, but he turned the truth on its head at least a couple of times too many. The multiple surprises at the ending were unbelievable and dissatisfying. Character development was sorely lacking, and it was sacrificed to increase the suspense and pace of the narrative, but that too, was not effective in my opinion.
On a positive note, I did enjoy the dual interpretations of the title as discerned by the hacker and the homicide detective. The title of the novel [THE BLUE NOWHERE] is interpreted by both team members. In Gillette’s coined phrase, “Blue” referred to the electricity that made computers work. “Nowhere” meant that it was an intangible place. The seasoned homicide detective renders his own analogy later in the book. He equated “Blue” for the uniform. The “Nowhere” because that place on the other side of the door you’re about to kick in, or down that alleyway, or in that front seat of the stopped car is different from anywhere else on God’s good earth.
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Encino Tg
A gem: Thrilling and engrossing
April 28, 2021
This book was published twenty years ago, so much of the computer technology is so dated as to make the reader laugh out loud, but the characters and plot are top notch. A great read that makes you think, trying to figure out what is what and trying to stay up with the minds of the protagonists. The clues are there, but easy to miss, which is why I found this to be challenging and rewarding.
Max Read
“A computer/hacker based mystery thriller”
January 8, 2012
“The Blue Nowhere” was written by Jeffery Deaver, a contemporary and popular mystery writer. Mr. Deaver has written numerous novels, several of which were made into movies or television specials. This book is of the mystery thriller genre of fictional literature. Bioactive Carboxylic Compound Classes
Overall this novel is a little light weight, but was quick and fun to read if you need a diversion. I would recommend it and rate it “Pleasurable not-memorable”.
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Dennis H. Kevonian
Solid Deaver
September 1, 2013
I enjoy almost all of Deaver’s characters and his interesting plot twists. Just when I think I’ve figured out what’s going to happen next, and to whom, Deaver surprises me with a real “flyer” from leftfield! It keeps me on edge and interested all through the novel. Bioactive Carboxylic Compound Classes PDF
I never want to give away plot detail which will ruin the reading experience for others, but I will state that this particular novel would be best understood by those with some familiarity with computers. Bioactive Carboxylic Compound Classes I can do a few basic things myself, but our protagonist in this novel has “mad” computer hacking skills, which he uses to battle with an antagonist with equal or perhaps even superior computer skills!
The novel seems to put forth the question, “Can an individual with such exceptional skill actually murder others using all that is known in the computer world? The Blue Nowhere??
I would definitely recommend this read for anyone who likes Deaver’s work, and the netherworld of computer gaming!
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Top reviews from other countries
AssaultonPrecinct13
I usually enjoy Jeffrey Deaver books BUT…
Reviewed in the United Kingdom on October 14, 2014
Bought the Kindle edition of this book and didn’t realise how old it was, which might explain why the continual explanations of computing terms seemed somewhat archaic. Bioactive Carboxylic Compound Classes Although elderly, I worked with computers every day so I’m not completely computer illiterate. The book started off very compelling but, by half way through the story, I had to resort to turning pages without reading all the explanations as I was so bored and just wanted to get back to the plot. Bioactive Carboxylic Compound Classes The book could have been reduced by 25% and retained my interest throughout but instead I only finished reading it through dogged perseverance rather than enjoyment. Loved Bishop the detective a lot and Gillette the hacker a little but didn’t really care about anyone else. How anyone’s managed to give it 5 stars beats me!
Alex
Definitely different
Reviewed in the United Kingdom on February 7, 2021
The last two Deaver books I have read are going in a different direction. Full of twists and interesting.
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